In the elderly, falls may occur as a result of benzodiazepines.

Benzodiazepines, including lorazepam, have been found to increase the risk of falls and fractures in the elderly. Do not give this medication to a child younger than 12 years old. Adverse effects including anterograde amnesia, depression and paradoxical effects such as excitement or worsening of seizures may occur. Withdrawal symptoms may include tremor, sweating, muscle cramps, stomach pain, vomiting, unusual thoughts or behavior, and seizure (convulsions). Blood or plasma lorazepam concentrations are usually in a range of 10-300 ug/L in persons either receiving the drug therapeutically or in those arrested for impaired driving, and 300-1000 ug/L in victims of acute overdosage. Store Ativan at room temperature away from moisture, heat, and light. Lorazepam was first introduced by Wyeth Pharmaceuticals in 1971 under the brand names of Ativan and Temesta. It is the classic way in which acute alcohol intoxication may affect a person. Dose requirements have to be individualized, especially in the elderly and debilitated patients in whom the risk of oversedation is greater. Because of its high potency, the smallest lorazepam tablet strength of 0.