Tell your doctor about any unusual or bothersome side effect.

Intravenous diazepam or lorazepam are first-line treatments for convulsive status epilepticus. They should also not drive, operate machinery, or use alcohol within this period. edit PharmacokineticsLorazepam is highly protein bound and is extensively metabolised into pharmacologically inactive metabolites. These effects are seen as more common with lorazepam than other benzodiazepines. Catatonia due to abrupt or too rapid withdrawal from benzodiazepines, as part of the benzodiazepine withdrawal syndrome, should also respond to lorazepam treatment. edit PharmacodynamicsRelative to other benzodiazepines, lorazepam is thought to have high affinity for GABA receptors, which may also explain its marked amnesic effects. edit WithdrawalOn abrupt, or overly rapid discontinuation of lorazepam, anxiety and signs of physical withdrawal have been observed, similar to those seen on withdrawal from alcohol and barbiturates. A large-scale, nationwide, U. How should I take Ativan?Take this medication exactly as it was prescribed for you. Lorazepam is sometimes used as an alternative to haloperidol when there is the need for rapid sedation of violent or agitated individuals, but haloperidol plus promethazine is preferred due to better effectiveness and due to lorazepam's adverse effects on respiratory function.